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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc3c552ef81af920d844ce08cbf08099a259fcf121a2a9538c0de92ad8201b64' 
  AND token = 'nIydi/LUqOHRHj2af7uIWn9XpclM5ND4mZkT72BcPN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}