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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd8e3ad3d5834d7ee49cf5b6bf7b10d2666c47f7cee0e7fbc9ce7ddfff602d21' 
  AND token = 'Jovy1IXtwb6n5a2PCtkGEf95XzVRkZIbjwhhwgNghTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}