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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '84cd7eedfb0e74ffaa3bb0419e270a18d4a9b4b014ea16d4f433e5435fa97349' 
  AND token = 'CB5ejOABxv07h1T6wSRBdSOgvpoaIowpi2zmhSUOrBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}