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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de9fde2fa6837f78c8d192a19fe45ce6a852a87ce840882531f38b243976ab18' 
  AND token = 'BmJT0m8pbkiXuK05EPMFkvvaTqyLaYkRgQ1hxzezv70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}