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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c05d1546eaae6415ebcece2266b730e534e238541d226559b3b49d18b999f0ea' 
  AND token = 'HwZF6qH2mv8F0E9V0yJmwUelHcEt0EA8F5sKi8dzOGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}