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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6821bd5f4159527c9308aa22483e4b1277e2e77accdd1b6c03425c3769c1d109' 
  AND token = 'd12MGM+AQwzcJ4uvQCkDwYpUmgwGg3kYxADO+vt0iSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}