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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a9e7af51a29f65ec5c3e32fc82970c1064cdde81c82d72300a3279c8475ddce' 
  AND token = 'x4uT+vXHBcqLoNk5TwAzv+CsbeEaMS31F5l7vj2qdOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}