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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '216b1a84ac5db8f012589bb42aa5a084e3e2abd0f432ffa21cabb18eaed2e2a2' 
  AND token = 'DmOpYNEkqHn45SrN83Krrj2wgh3vKgSfnhbpgR25M4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}