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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3c401aa5c375be58d24d10b7b22922be878746618bdddaefa33af34e614bab0' 
  AND token = '2V1M2A5E3/PZ6N4bHGI+j81ZgHuVnBe0fvixJsNtBhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}