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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e46d3c9e73486eb02c2b78e3b5f2171965bbb007ca57d2a15830f8956dc04cd4' 
  AND token = 'ZEh95zWVofEXfCk1LJbiaJ89KyrHLApFHD1y02LPxiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}