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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f78b53499c2842dc85ef355fb42ecc5e713f0f20a35718a46c9305e3b95aab34' 
  AND token = 'Er4IzZr8Y5sFOerbgfs03KktKoMBTuvWl7YdkaEQq4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}