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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef64ab6351151d22f8c8b6446cb3815ea69436302ce4548f809057167f254d80' 
  AND token = 'OrJZYgNtXIoIF9WMzokbNMM4g5Y5DZVOrfh4MCCVPN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}