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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a403be4c9d0aa31f82873e4e2085c31c3e83199955ab38cdced9bec97104bd4' 
  AND token = 'bIyouXpKDOUjD+L9ZUyYpqOk0ZC/hHM7RWbDqGpZ0Hg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}