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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '860990b3792276bf020f01dc86b4217d78243ebd7e4e134e3294f39e6bbf3b49' 
  AND token = 'YwZLHe8FQyZWexhkRwhPtNn0W3CP5tHe9HszTOrJo1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}