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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26ee0291b24915a141fff1796f0607f9a28b4b391e7cddf2c81bb14b82a74d23' 
  AND token = 'NbFPcmLKK5HT3jKFAEgFeVIWSLOAcoMJh1yBFxwBFk4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}