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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72ebf1f1f5b002e6eeb67a034a9ef9870281203455c4ae66839f1c24e14ef7fe' 
  AND token = 'tiJ3Ganwu3TcoF63Mq5FUlTHlUitVm0RteIVJYkxWPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}