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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19a6842bc648dc54c1887e32959f7f190d27d8913585758eedc3cfe6249de10e' 
  AND token = 'cZ63JZ0MkSTeD9NFa1Os5T2e7xX8g3ZtGTSo6OItgWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}