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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c20dfdcb021d80615ac979413228e02ccc7a1e1884851d153ea4e7172c43748c' 
  AND token = 'A8mVaQx/9m12kVA3MGBIvKDfrWq/MIRYyGyS4PbTY28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}