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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a63a8fbf8378a2c52a6e635f77e62e4eb46717f471b4bead371611df276d6a6' 
  AND token = 'fsCfYoU1BCTf8hq1pxo9lwsbwB3jIFz/Ae0qBhZDnyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}