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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00c448dc69a19f2342fede33d7d381e23be1451dfdc52443eebb443208f32b66' 
  AND token = '0EHzHru64EuRa4FjXej0qpLy8C1XA7k34+nB8MpN6/U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}