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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43fd0f0992f0eea8ae2d5d744321aa8b0eb33675c0dcaf90006c96863fe7bf60' 
  AND token = 'j6UaAlnnp8qXsgkyGt2feIT9KVBqKIQ4MIIKJ4Mfy0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}