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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59a890687c241f42344ba589b4c76069394bc91f0cd9181a4cdfcfdeb3db3421' 
  AND token = '8c9YSN0qLFKxTM4TmQZNckKHKZU+GSj+wCul59ftFEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}