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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1818e42b63e9e69a5e21d702ae3589ffee3090e8d528527f58a5e42bf9a2e203' 
  AND token = '0mFz/RHXLxcP8rwPPIgOGSELz6IGKIifasFmOgdRXPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}