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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1eb17b77dbd3725c78bcd8bafbb43ee49f6e05df1f2e6b23b714160f783005de' 
  AND token = 'Xuyo6bDbBOHXf+BZN778xRqP3ohal/HgvkFFjMBsOZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}