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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be12345e2db102402e8a249c2dccc5b61122857a48550ff92be500dc8c2f1ed2' 
  AND token = 'thiS8+Kdprf7x49ViD3L7aQ9aDxihVcXQJj+ATA9kr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}