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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6b8d9410fce5b1e30f3f8a7ca725e13025122d33cff80cc77099b00a46282e4' 
  AND token = '4KCzqp2VYeRMLz5MURD6e7UUvxXqMdA0Nnw64HOLouk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}