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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d32eaccead497ae525ad1bce0a5dffef7c1f4d465d7e308a3c1f9324df8fd41' 
  AND token = 'dDuz5FHRZ/SjknrN/mO6BM2sKeD0x7VAdi2wpB663H8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}