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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cd3783c71009d625375e42f22fa04ede3b7d10ecb7d9645aa0a626776108118' 
  AND token = 'O7hPPZ3ZesC4ART1EQkuFTctnZD6hWBs/AWjWG4ppzY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}