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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e27fdfe89f17d26e4703502a5ff0a6547d4beba7d21deb1f4acefd315d477b1' 
  AND token = 'IaxEMpbhmz6a98zdAB+jO/KCeXmgaVP7zPAofZy+HP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}