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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d4af8de323265a13e816d03f00a61f25dedda2e0dfb92a1f931a79ab457b191' 
  AND token = '55VMjr/ZqmOhL4MLTXPFchQcwK/STB4OXJ3Ko2IkW24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}