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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3d302fca513987a5caae0054baf39ce0ba1183998f1a545d0061e1bde29bce8' 
  AND token = 'paIP2v7K7MBRVBJSy038JbexqLT/d14u+eEeOQazxXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}