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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88de8a95c43330f3c10b0ac9f424abd07a149e6f92d3f48f752bb497cc88de31' 
  AND token = 'qeNQQ+VKRmmHqomm9/kdnW2NAZc9ISO/opGfD4gfET0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}