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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '484a8530a053b029debe5beac58cc34045951c550da41c112862a6ab82eaf00a' 
  AND token = '1nS1yqCY/s4iLPlXXbImKmtvfeC03xkUzVCHgOZm0K4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}