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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3535ddfa32d83878018ed35ad06701daa6f4addc41f5714608026e0c1e3affe4' 
  AND token = 'AUJiUMj2wks+rdFa/ThVcUxVviahq86CGYJaUIax8cQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}