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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6f9b2a50a5b9f6d633215deaf6943f62340a664498d83128e4491467d2f0fa0' 
  AND token = '6DWaN1xu1FcDSS+RzDgfa48b5uxgYlYgbXn+BqFFjbo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}