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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a41b4f59e9abb568c72d04a2a8dc2a4c89bd23e7e51bdd7fe239501893dfa431' 
  AND token = 'ecWxg8jGmyz/q1CcWhcp12pO+P6wiT1SXLk2agOZG+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}