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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c33a79e5d06835af8fb8901bb856900501178c946625a0821db9a7959e31004f' 
  AND token = 'v1vC6Nl+yVcXmxq/lGkYex6Sl+lm7EU4tuFXg7hZ0iM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}