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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '708c2a1bb5eec52b5943f803a18e13945b77b090c4dfc95e0b6678056a3db59c' 
  AND token = 'rTJglJtr1yAD6RwDrpLUNj+goZUHULTELmZhsWmwiSQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}