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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf4f9e04f24f6298101f690a3a3dca00ca04e6e4133ed68b543e091f227d7ff1' 
  AND token = 'faMoUgwG/Rriz7H60ooO7vBCuCXEfvHS+XQs8dHc2rU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}