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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '129f74cbd009bb31911e2ba8f865a66f5f5dd8b262411ee8e16db50a17ae3362' 
  AND token = 'LsSN0Ib6GLm+PtnZbydjBvBgRhiQC6vGJP+PdIZDRZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}