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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a053f7cb7392d5c6221c0b80c7095a598211fd1b9402bb43f15d1d2c1c622d84' 
  AND token = 'XPKabOTRhjTW3x7a/au/72IJqmdhk+qywMdhFcM9yKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}