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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ec0e85ccfc7727289813702350c2fa1eab5b47c2b5313d9a5734cdc93a5f0cd' 
  AND token = '2u8zQkR9Wbd3x5u5Apj+fgca97gwzSGFbdDRagFSwNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}