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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f962851a3df50b0600be0621c5d73b88df3b6b586a6f3b452ecb0795b014c72c' 
  AND token = '+806nedOsK6s7XEDcF/mL0PPWZgwwdv4NfNu3sjMlhM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}