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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57a01ebc38d4a4bb6619a3ba1ad2c41129ea37863ccf5b3537948ac6d551d138' 
  AND token = 'Y9ePD2GueokQnDIqEcJUm6wx7rEJL3cmFnKBw0UJscs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}