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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c81d3eb607a7a71f313b6d2535fbfa6471fc63ebe613b22cb82a784dc14e22e' 
  AND token = 'QQ45Z0DTk4uRrsCYte2by5rxn6yV6KeeUVXaGsAmCdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}