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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '450400d974a019709489ce8f119ff5029ff0b5e516f47bc1fe80fa00d6ff83f5' 
  AND token = 'SaSj9cxTmA0Qdj6yXm8XzlqnIPzonuifaeacMylY7Ws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}