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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '934bc60b3912240a4c4a597f0d30fa2081f3a76fac4d953e7f4b2c69cd15dff8' 
  AND token = 'cA1JfDkrm2HMV/dwrLxTaHOp4XE+gj8X2EwNP/iyBp8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}