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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4abfbc0a00f9ce5179e1820b0cbf5ce5e13a1ffc99feb8dd43eb856619e32199' 
  AND token = 'hC8yA7paOvG29WuXSDumgXNoZ5WQ6Nhlyj+AdYJj2q0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}