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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '661335df58f4ce6f0d0ab22fa0e403cc0dfc7f4e4e7caa0f48a688794f825776' 
  AND token = 'aMkrzfWRQJJzQAtbHGlcUUI/BwYFwVS6MxCatclHRjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}