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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e307710b7a30f58836c7317f48335316878b572199bb57f2d8f287f7321ef2b6' 
  AND token = '0f1MHbFP69nMiJB2D8AR/nE0cqf/ZfkweItu9gWV7uA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}